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Br J Ophthalmol 2003;87:1429-1430 doi:10.1136/bjo.87.11.1429
  • Letter

Bilateral Aspergillus endophthalmitis in a patient with chronic lymphocytic leukaemia

  1. O de O Machado1,
  2. R Gonçalves1,
  3. E M Fernandes1,
  4. W R Campos1,
  5. F Oréfice1,
  6. A L L Curi2
  1. 1Department of Ophthalmology, Federal University of Minas Gerais, Brazil
  2. 2Department of Ophthalmology, Federal Fluminense University Niterói, Brazil
  1. Correspondence to: André L L Curi R Francisco Dutra 163/701, Icaraí, Niterói, RJ, Brazil Cep 24220150; curiallyahoo.com
  • Accepted 30 March 2003

Aspergillus species are ubiquitous saprophytic moulds, commonly growing in soil, stored hay, and decaying vegetation. Even though exposure to Aspergillus is universal, infection in humans is uncommon.1Aspergillus infection of ophthalmic interest usually causes keratitis or orbital cellulitis; Aspergillus endophthalmitis is a relatively rare condition that has a devastating course, with blindness as its usual outcome.2 The clinical diagnosis is difficult and the treatment is disappointing. In most cases, ocular involvement results from spread of aspergillosis infection from others organs and typically occurs in injecting drug users and in patients with immune deficiency of various causes. The leucopenia appears to be a predisposing condition for the occurrence of aspergillosis.3

We report an unusual case of bilateral endogenous Aspergillus endophthalmitis in a patient with chronic lymphocytic leukaemia in the absence of any detectable focus of aspergillosis …

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