rss
Br J Ophthalmol 2003;87:147-148 doi:10.1136/bjo.87.2.147
  • Scientific correspondence

Community treatment with azithromycin for trachoma is not associated with antibiotic resistance in Streptococcus pneumoniae at 1 year

  1. B D Gaynor1,
  2. K A Holbrook2,
  3. J P Whitcher1,
  4. S O Holm3,
  5. H C Jha4,
  6. J S P Chaudhary4,
  7. R C Bhatta4,
  8. T Lietman1
  1. 1The Francis I Proctor Foundation and the Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA
  2. 2Community Health Epidemiology and Disease Control, San Francisco Department of Public Health, San Francisco, CA, USA
  3. 3The Francis I Proctor Foundation
  4. 4Geta Eye Hospital, Geta, Nepal
  1. Correspondence to: Bruce D Gaynor, MD, The Francis I Proctor Foundation and the Department of Ophthalmology, UCSF Medical Center, San Francisco, CA 94143–0944, USA; bgaynor{at}itsa.ucsf.edu
  • Accepted 19 March 2002

Abstract

Aims: To determine if macrolide resistant Streptococcus pneumoniae will be a major concern in areas that receive annual mass azithromycin distributions for trachoma.

Methods: A cross sectional survey was conducted of nasopharyngeal S pneumoniae isolates for susceptibility to azithromycin 1 year after administering a single dose of azithromycin to treat trachoma in a village in Nepal.

Results:S pneumoniae was isolated from 50 (86%) of 57 nasopharyngeal cultures and no resistance to azithromycin was detected.

Conclusion: The authors were unable to demonstrate that mass azithromycin therapy for trachoma produced macrolide resistant S pneumoniae that persists until the next scheduled annual treatment.

Footnotes

    This Article

    1. Abstract
    2. Full text
    3. PDF

    Services

    1. Email this link to a friend
    2. Alert me when this article is cited
    3. Alert me if a correction is posted
    4. Alert me when eletters are published
    5. Article Usage Statistics
    6. Similar articles in this journal
    7. Similar articles in Web of Science
    8. Similar articles in PubMed
    9. Add article to my folders
    10. Download to citation manager
    11. Request permissions

    Responses

    1. Submit a response
    2. No responses published

    Social bookmarking

    Register for free content


    Free sample
     This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
    View free sample issue >>

    Free archive
    The full back archive is now available for BJO. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006, back to volume 1 issue 1.
    Register to access the free archive >>

    Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.