Table 3
Families and sporadic reports of disorders similar to MRCS
| Author(s) | Inheritance of trait | No affected | Clinical features | Chromosomal location | Gene involved |
|---|---|---|---|---|---|
| Hermann33 | AD | 13 | Microphthalmia, moderate myopia +/− retinitis pigmentosa | ? | |
| Mackay20 | AR | 7 | Nanophthalmos, retinal degeneration, angle closure glaucoma | ? | |
| Bateman34 | AD | 4 | Microcornea, coloboma, posterior staphyloma | ? | |
| Bessant et al25 | AR | 6 | Microphthalmia, scleroderma, nystagmus | 14q32 (CMIC) | ? |
| Percin et al2 | AR (2 families) | 4 and 1 | Microphthalmia, bilateral iris coloboma, cataracts | 14q23.3 | CHX10 |
| Othman et al23 | AD | 16 | Nanophthalmos | 11p12-q13 (NNO1) | ? |
| Morle26 | AD | 9 | Colobomatous microphthalmia | 15q12-q15 (NNO2) | ? |
| Buys21 | Sporadic | 1 | Nanophthalmos, retinitis pigmentosa, disc drusen | ? | |
| Ghose et al22 | Sporadic | 1 | Nanophthalmos, microcornea, pigmentary retinal dystrophy | ? |
