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Br J Ophthalmol 87:240 doi:10.1136/bjo.87.2.240
  • Letter

Merkel cell carcinoma of the eyelid in association with chronic lymphocytic leukaemia

  1. N Sinclair1,
  2. K Mireskandari1,
  3. J Forbes1,
  4. J Crow2
  1. 1Department of Ophthalmology, Royal Free Hampstead NHS Trust, London, UK
  2. 2Department of Histopathology, Royal Free and University College Medical School, London, UK
  1. Correspondence to: Dr Sinclair; sinclne{at}hotmail.com
  • Accepted 13 May 2002

Merkel cell carcinoma (MCC) is a rare skin neoplasm. Tang and Toker1 first described MCC in 1978 and since then 19 cases in association with chronic lymphocytic leukaemia (CLL) have been reported.2–5 To the best of our knowledge, involvement of the eyelid by MCC has never been reported in the literature in association with CLL.

Case Report

An 84 year old white man was referred with an 8 week history of a painless lump on his right upper eyelid (Fig 1A). He was complaining of visual obscuration secondary to a mechanical ptosis. Ophthalmic history was unremarkable and specifically there were no previous chalazions or trauma. On examination a firm lesion of the right eyelid measuring 2 × 1 cm with overlying telangiectatic vessels and sparing of the eyelashes was noted (Fig 1A). Further ophthalmic examination was unremarkable. General …

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