Measurement of the cerebrospinal fluid pressure usually requires a lumbar puncture or craniotomy to get direct access to the cerebrospinal fluid space. These techniques, however, are invasive and so carry the risk of complications such as infections and damage to the neural structures. Furthermore, owing to the leakage of cerebrospinal fluid during the puncture, the cerebrospinal fluid pressure will be altered in the moment the measurement is performed. It is, therefore, desirable to have a non-invasive method allowing the estimation of the intracerebral pressure without requiring a direct access to the brain or spinal cord. We describe a patient in whom ophthalmodynamometry strongly suggested an increased intracerebral pressure which was confirmed by eventual direct measurement.