rss
Br J Ophthalmol 87:403-408 doi:10.1136/bjo.87.4.403
  • Scientific correspondence

Associations of selected medications and visual function: the Beaver Dam Eye Study

Table 2

Self assessed visual function by drug use. The Beaver Dam Eye Study, 1993–5

Taking No None of the time Little or some of the time Most or all of the time p Value*
*Mantel-Haenzsel adjusted for age.
*=Mantel-Haenzsel adjusted for age. †Corresponds to the question “In general, would you say your vision was excellent, very good, good, fair, or poor?”
Vision limted when:
Driving at night
    High blood pressure medication No 1777 66.74 30.95 2.31
Yes 1137 62.80 34.48 2.73 0.258
    Barbiturates No 2878 65.25 32.35 2.40
Yes 44 59.09 34.09 6.82 0.207
    Antidepressant No 2799 65.56 32.12 2.32
Yes 123 56.10 38.21 5.69 0.013
    Antipsychotic No 2889 65.32 32.29 2.39
Yes 33 51.52 39.39 9.09 0.035
    Antianxiety No 2710 65.65 32.21 2.14
Yes 212 58.96 34.43 6.60 0.011
    Benzodiazepines No 2715 65.64 32.19 2.17
Yes 207 58.94 34.78 6.28 0.015
    Glaucoma drops No 2807 65.30 32.24 2.46
Yes 68 58.82 38.24 2.94 0.631
    Narcotic analgesic No 2843 65.28 32.33 2.39
Yes 79 60.76 34.18 5.06 0.294
    Aspirin No 1758 66.78 30.83 2.39
Yes 1160 62.84 34.57 2.59 0.134
    Cardiac medication No 2828 65.28 32.28 2.44
Yes 94 61.70 35.11 3.19 0.940
    Oral hypoglycaemics No 2811 65.64 31.87 2.49
Yes 111 53.15 45.05 1.80 0.045
    Insulin No 2859 65.13 32.35 2.52
Yes 63 66.67 33.33 0.00 0.450
    Multivitamins Never 858 70.51 27.86 1.63
Past 723 64.73 32.92 2.35 <0.001
Current 1334 62.07 34.86 3.07
Reading regular newsprint
    High blood pressure medication No 2093 89.01 8.79 2.20
Yes 1585 84.73 10.85 4.42 0.022
    Barbiturates No 3637 87.41 9.57 3.02
Yes 56 73.21 16.07 10.71 0.002
    Antidepressant No 3495 87.47 9.56 2.98
Yes 198 82.32 11.62 6.06 0.131
    Antipsychotic No 3629 87.30 9.62 3.09
Yes 64 81.25 12.50 6.25 0.344
    Antianxiety No 3361 87.71 9.43 2.86
Yes 332 81.93 12.05 6.02 0.011
    Benzodiazepines No 3358 87.94 9.32 2.74
Yes 335 79.70 13.13 7.16 <0.001
    Glaucoma drops No 3516 87.83 9.36 2.82
Yes 113 71.68 18.58 9.73 <0.001
    Narcotic analgesic No 3564 87.49 9.71 2.81
Yes 130 78.46 9.23 12.31 <0.001
    Aspirin No 2243 87.52 9.23 3.25
Yes 1446 86.65 10.37 2.97 0.882
    Cardiac medication No 3509 87.77 9.26 2.96
Yes 184 76.09 17.39 6.52 0.045
    Oral hypoglycaemics No 3533 87.57 9.40 3.03
Yes 161 78.26 16.15 5.59 0.012
    Insulin No 3586 87.65 9.37 2.98
Yes 108 71.30 20.37 8.33 <0.001
    Multivitamins Never 1030 87.67 10.00 2.33
Past 905 86.41 10.28 3.34 0.619
Current 1746 87.34 9.22 3.44
Reading road signs
    High blood pressure medication No 2090 92.54 6.36 1.10
Yes 1577 89.41 8.69 1.90 0.129
    Barbiturates No 3625 91.26 7.31 1.43
Yes 57 85.96 12.28 1.75 0.368
    Antidepressant No 3484 91.30 7.41 1.29
Yes 198 88.89 7.07 4.04 0.257
    Antipsychotic No 3620 91.24 7.40 1.35
Yes 62 87.10 6.45 6.45 0.127
    Antianxiety No 3353 91.47 7.19 1.34
Yes 329 88.15 9.42 2.43 0.156
    Benzodiazepines No 3349 91.61 7.26 1.13
Yes 333 86.79 8.71 4.50 0.002
    Glaucoma drops No 3507 91.56 7.16 1.28
Yes 111 80.18 15.32 4.50 0.008
    Narcotic analgesic No 3553 91.36 7.26 1.38
Yes 129 86.05 10.85 3.10 0.109
    Aspirin No 2233 91.54 6.90 1.57
Yes 1445 90.59 8.17 1.25 0.971
    Cardiac medication No 3500 91.43 7.17 1.40
Yes 182 86.26 11.54 2.20 0.775
    Oral hypoglycaemics No 3523 91.51 7.04 1.45
Yes 159 83.65 15.09 1.26 0.040
    Insulin No 3575 91.30 7.30 1.40
Yes 107 86.92 10.28 2.80 0.250
    Multivitamins Never 1027 92.79 6.13 1.07
Past 905 90.50 7.62 1.88 0.126
Current 1737 90.56 8.06 1.38
Reading small print
    High blood pressure medication No 2092 73.66 21.51 4.83
Yes 1585 68.39 23.26 8.34 0.056
    Barbiturates No 3633 71.70 22.16 6.14
Yes 57 54.39 28.07 17.54 0.001
    Antidepressant No 3493 71.77 22.22 6.01
Yes 197 65.48 22.84 11.68 0.081
    Antipsychotic No 3627 71.66 22.08 6.26
Yes 63 58.73 31.75 9.52 0.149
    Antianxiety No 3359 72.64 21.49 5.86
Yes 331 59.21 29.91 10.88 <0.001
    Benzodiazepines No 3355 72.70 21.61 5.69
Yes 335 58.81 28.66 12.54 <0.001
    Glaucoma drops No 3514 72.23 22.05 5.72
Yes 112 55.36 26.79 17.86 0.002
    Narcotic analgesic No 3560 71.83 22.30 5.87
Yes 130 60.77 20.77 18.46 <0.001
    Aspirin No 2241 71.53 21.82 6.65
Yes 1445 71.21 22.98 5.81 0.354
    Cardiac medication No 3505 72.10 22.03 5.88
Yes 185 58.92 26.49 14.59 0.033
    Oral hypoglycaemics No 3529 71.83 22.10 6.06
Yes 161 62.73 25.47 11.80 0.026
    Insulin No 3583 72.01 21.99 6.00
Yes 107 52.34 30.84 16.82 <0.001
    Multivitamins Never 1029 72.59 22.25 5.15
Past 905 70.72 23.20 6.08 0.282
Current 1743 71.20 21.80 7.00
Recognising people across the street
    High blood pressure medication No 2094 89.30 8.83 1.86
Yes 1579 85.18 11.21 3.61 0.146
    Barbiturates No 3632 87.58 9.80 2.62
Yes 56 83.93 12.50 3.57 0.619
    Antidepressant No 3494 87.86 9.67 2.46
Yes 194 81.44 12.89 5.67 0.039
    Antipsychotic No 3624 87.61 9.80 2.59
Yes 64 82.81 12.50 4.69 0.577
    Antianxiety No 3356 88.35 9.24 2.41
Yes 332 79.22 15.96 4.82 <0.001
    Benzodiazepines No 3352 88.63 9.13 2.24
Yes 336 76.49 16.96 6.55 <0.001
    Glaucoma drops No 3513 88.13 9.59 2.28
Yes 112 69.64 19.64 10.71 <0.001
    Narcotic analgesic No 3562 87.82 9.66 2.53
Yes 127 79.53 14.96 5.51 0.031
    Aspirin No 2239 88.03 9.33 2.64
Yes 1445 86.71 10.66 2.63 0.867
    Cardiac medication No 3507 87.97 9.52 2.51
Yes 181 79.01 16.02 4.97 0.385
    Oral hypoglycaemics No 3528 87.98 9.58 2.44
Yes 161 77.64 15.53 6.83 0.001
    Insulin No 3581 87.99 9.52 2.49
Yes 108 72.22 20.37 7.41 <0.001
    Multivitamins Never 1027 89.87 8.57 1.56
Past 904 87.39 9.85 2.77 0.005
Current 1744 86.18 10.61 3.21
Self reported visual function† Excellent/very good Good/fair Poor
    High blood pressure medication No 2101 14.33 74.44 11.23
Yes 1588 10.58 73.55 15.87 0.164
    Barbiturates No 3647 12.81 74.03 13.16
Yes 57 8.77 70.18 21.05 0.143
    Antidepressant No 3503 12.90 74.28 12.82
Yes 201 9.95 68.66 21.39 0.040
    Antipsychotic No 3637 12.76 74.15 13.09
Yes 67 11.94 64.18 23.88 0.293
    Antianxiety No 3370 13.00 74.36 12.64
Yes 334 10.18 70.06 19.76 0.044
    Benzodiazepines No 3366 13.16 74.39 12.45
Yes 338 8.58 69.82 21.60 0.001
    Glaucoma drops No 3528 12.81 74.35 12.84
Yes 113 3.54 69.03 27.43 0.004
    Narcotic analgesic No 3575 12.70 74.38 12.92
Yes 130 13.85 63.08 23.08 0.252
    Aspirin No 2251 13.15 74.81 12.04
Yes 1449 12.08 72.67 15.25 0.128
    Cardiac medication No 3517 13.25 74.18 12.57
Yes 187 3.21 70.05 26.74 0.001
    Oral hypoglycaemics No 3544 12.98 74.18 12.84
Yes 161 7.45 69.57 22.98 0.006
    Insulin No 3596 13.01 74.14 12.85
Yes 109 3.67 68.81 27.52 <0.001
    Multivitamins Never 1032 12.60 73.26 14.15
Past 906 13.25 74.06 12.69 0.320
Current 1752 12.61 74.37 13.01

This Article

  1. Abstract
  2. Full text
  3. PDF

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.