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Br J Ophthalmol 87:413-419 doi:10.1136/bjo.87.4.413
  • Scientific correspondence

Comparison of algorithms for detection of localised nerve fibre layer defects using scanning laser polarimetry

Table 4

Areas under the receiver operating characteristic (ROC) curves for discriminating between healthy (n=53) and glaucomatous (n=48) eyes with localised nerve fibre layer defects. Sensitivities at fixed specificities

Area under ROC curve (SE) Sens/Spec (spec=90%) Sens/Spec (spec=80%)
*Linear discriminant function obtained from sectoral based analysis.
†Linear discriminant function obtained from Fourier analysis.
‡Linear discriminant function from Weinreb et al.17
LDF sectoral* 0.93 (0.03) 81/91 90/81
LDF Fourier† 0.93 (0.03) 71/91 97/81
LDF Weinreb‡ 0.86 (0.04) 52/91 77/81
The number 0.76 (0.05) 40/91 50/81
Inferior ratio 0.78 (0.05) 40/91 58/81
Inferior average 0.82 (0.04) 35/91 75/81
Ellipse average 0.75 (0.05) 27/91 44/83
Max modulation 0.73 (0.05) 29/91 46/81
Average thickness 0.71 (0.05) 23/91 42/81
Superior average 0.71 (0.05) 25/91 29/81
Superior integral 0.69 (0.05) 19/91 46/81
Ellipse modulation 0.69 (0.05) 15/93 46/83
Symmetry 0.69 (0.05) 23/92 46/83
Superior ratio 0.64 (0.06) 29/91 33/81
Superior/nasal 0.63 (0.06) 19/91 31/81

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