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Br J Ophthalmol 87:488-492 doi:10.1136/bjo.87.4.488
  • Original Article
    • Laboratory science

Laser photocoagulation alters the pattern of staining for neurotrophin-4, GFAP, and CD68 in human retina

Table 2

Immunohistochemical staining of lasered and control retinas

Specimen number Origin of specimen Laser before enucleation (days) NT4 GFAP CD68
Intensity of staining: +++ = strong, ++ = moderate, + = mild, − = negative. *Staining reduced in outer nuclear layer at the site of the laser burn, †staining of inner and outer nuclear layers of the retina, ‡staining throughout the whole retina, §scattered staining of cells predominantly in the nerve fibre layer.
1 Melanoma 1 +* +++‡ +
2 Melanoma 2 +* +++‡ +
3 Melanoma 6 +* +++‡ ++
4 Melanoma 6 +* +++‡ ++
5 Melanoma NA +† +++‡
6 Melanoma NA +† +++‡
7 Melanoma NA +++‡
8 Cadaveric donor NA ++†
9 Cadaveric donor NA ++†
10 Cadaveric donor NA ++†

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