Long term survival of patient with invasive aspergillosis involving orbit, paranasal sinus, and central nervous system
- K Kusaka1,
- I Shimamura2,
- Y Ohashi2,
- S Ota3
- 1Division of Ophthalmology, Matsuyama Red Cross Hospital, Bunkyo-cho 1, Matsuyama City, Ehime 790-0826, Japan
- 2Department of Ophthalmology, Ehime University School of Medicine, Shizugawa, Shigenobu-cho, Onsen-gun, Ehime 791-0295, Japan
- 3Department of Neurological Surgery, Ehime University School of Medicine, Shizugawa, Shigenobu-cho, Onsen-gun, Ehime 791-0295, Japan
- Correspondence to: Kanae Kusaka, MD, PhD, Tane Memorial Eye Hospital, 1-1-39, Sakaigawa, Nishi-ku, Osaka 550-0024, Japan; kkusaka{at}tcct.zaq.ne.jp
- Accepted 2 October 2002
Aspergillus infections of the paranasal sinuses are classified as invasive or non-invasive.1 The vast majority are non-invasive with a good prognosis; however, the invasive type behaves as a malignant neoplasm with bone destruction, orbital and intracranial extensions, and a high mortality rate.2–4
We present one patient with invasive paranasal aspergillosis that extended into the orbit and cranial cavities, and who has survived for 9 years and 1 month.
Case report
Along with headaches and periorbital pain beginning in July 1993, a 64 year old woman noticed a decrease vision in her right eye and visited us on 7 September 1993. She had poorly controlled diabetes mellitus. Her corrected visual acuity was 20/30 right eye and 20/20 left eye, and her critical flicker fusion frequency was 25 Hz right eye and 32 Hz left eye. A central scotoma with a relative afferent pupillary defect was present in the right …
