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Br J Ophthalmol 2003;87:796-797 doi:10.1136/bjo.87.6.796
  • Letter

Successful photodynamic therapy for subretinal neovascularisation due to Sorsby’s fundus dystrophy: 1 year follow up

  1. S C Wong1,
  2. K C S Fong1,
  3. N Lee1,
  4. K Gregory-Evans1,
  5. C Y Gregory-Evans2
  1. 1Western Eye Hospital, Marylebone Road, London NW1 5YE, UK
  2. 2Department of Cell and Molecular Biology, Faculty of Medicine, Imperial College, Exhibition Road, London, UK
  1. Correspondence to: Mr Kevin Gregory-Evans, Western Eye Hospital, Marylebone Road, London NW1 5YE, UK; k.gregory-evans{at}ic.ac.uk
  • Accepted 27 November 2002

Sorsby’s fundus dystrophy (SFD) is a rare but severe autosomal dominant disease. Clinically it is characterised by severe central visual loss, mainly due to submacular choroidal neovascularisation (CNV) during the fourth or fifth decade of life.1,2 Blindness therefore occurs during the patient’s most productive years of employment. We report a case of successful treatment of CNV in SFD with photodynamic therapy (PDT) and verteporfin.

Case report

A 40 year old white man (occupation photographer) presented in 1999 with sudden blurring and distortion of vision in the right eye. Visual acuity was 6/6 in the right eye, and 6/4 in the left. Funduscopy and fundus fluorescein angiogram (FFA) demonstrated a large subfoveal CNV. This was deemed unsuitable for laser photocoagulation owing to its location and size. Subsequently, acuity in the right eye deteriorated to 3/60 with the formation of a disciform macular …

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