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Br J Ophthalmol 88:145-151 doi:10.1136/bjo.88.1.145
  • Perspective

Protein kinase C inhibition and diabetic retinopathy: a shot in the dark at translational research

Table 1

PKC is a family of isoenzymes, divided into three groups according to cofactor (Ca2+) and phospholipid (PL) requirements

Group A Group B Group C
Classic (cPKCs) Novel (nPKCs) Atypical (aPKCs)
*PKC-λ and PKC-ι may be species homologues.
Ca2+ and PL dependent Ca2+ independent and PL dependent Ca2+ and PL independent
α δ ι
βI ε λ*
βII η ζ
γ θ
μ

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