Table 1

Vancomycin concentrations in corneal stroma of study group

No	Sex	Birth year	Diagnosis*	Corneal weight (gr)	Vanco** μg/ml	Vanco per tissue (μg/g)	Protein (mg/ml)	Vanco per protein (μg/ml)
*Stromal oedema was caused by pseudophakic bolus keratopathy.
**All corneas were diluted with 2.0 ml.
1	M	1927	Leukoma	0.0377	1.70	90.19	0.680	2.50
2	M	1940	Stromal oedema	0.0377	0.59	31.30	0.730	0.81
3	M	1971	Keratoconus	0.0403	1.10	54.59	0.810	1.36
4	M	1968	Keratoconus	0.0336	0.80	47.62	0.880	0.91
5	F	1976	Keratoconus	0.0384	0.65	33.85	0.665	0.98
6	M	1927	Stromal oedema	0.0366	0.98	53.55	0.530	1.85
7	F	1929	Stromal oedema	0.0421	0.60	28.50	0.590	1.02
8	F	1921	Stromal oedema	0.0362	1.23	67.68	0.475	2.58
9	F	1924	Stromal oedema	0.0429	1.04	48.48	0.600	1.73
10	F	1921	Stromal oedema	0.0511	1.70	66.54	0.886	1.92
11	F	1921	Stromal oedema	0.0369	0.64	34.69	0.722	0.89
12	M	1920	Stromal oedema	0.0239	0.88	73.64	0.781	1.13
13	F	1922	Stromal oedema	0.0475	1.70	71.58	0.866	1.96
14	M	1949	Keratoconus	0.0399	0.60	30.08	0.828	0.72
15	M	1942	Stromal oedema	0.0393	0.88	44.78	0.887	0.99
16	F	1925	Fuchs’ dystrophy	0.0340	0.46	27.06	0.991	0.46
17	M	1930	Failed graft	0.0389	1.70	87.40	0.900	1.89
18	M	1941	Failed graft	0.0416	0.76	36.54	0.727	1.05
19	M	1930	Failed graft	0.0396	0.64	32.32	0.787	0.81
20	M	1926	Leukoma	0.0615	0.46	14.96	0.557	0.83
21	F	1974	Keratoconus	0.0279	0.62	44.44	0.635	0.98
22	F	1925	Stromal oedema	0.0307	0.47	30.62	0.600	0.78
23	M	1968	Keratoconus	0.0322	0.70	43.48	0.720	0.97
24	M	1980	Keratoconus	0.0451	0.61	27.05	0.670	0.91

Human corneal stromal tissue concentration after consecutive doses of topically applied 3.3% vancomycin

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