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Br J Ophthalmol 88:72-74 doi:10.1136/bjo.88.1.72
  • Clinical science
    • Scientific reports

The relation of Graves’ ophthalmopathy to circulating thyroid hormone status

Table 2

Data recorded for ALTH and NLTH groups

ALTH group (n = 413) NLTH group (n = 69) p Value
Age (years) at first neuro-ophthalmology visit 52.0 (15.4) 56.0 (13.5) 0.02
Age (years) at first ocular dysfunction 49.0 (15.6) 54.4 (13.4) 0.004
Difference between age at 1st neuro-ophthalmology visit and 1st ocular dysfunction 2.7 (5.3) 1.3 (2.5) 0.02
BMI 23.4 (4.0) 26.3 (5.6) <0.001
Age adjusted (mean (SE)) 23.4 (0.3) 26.1 (0.8) 0.001
Sex
    Male 98 (24%) 34 (49%) <0.001
    Female 315 (76%) 35 (51%)
Race
    White 249 (60.3%) 43 (62.3%) 0.34
    African-American 27 (6.5%) 2 (2.9%)
    Hispanic 31 (7.5%) 9 (13.0%)
    Asian 43 (10.4%) 4 (5.8%)
    Other 63 (15.3%) 11 (15.9%)
Medical treatment for ophthalmopathy 140 (34%) 17 (25%) 0.17
Eye surgery 217 (53%) 23 (33%) 0.004
Autoimmune 17 (4%) 5 (7%) 0.23
Family history thyroid disease 99 (24%) 7 (10%) 0.01
History of radiation treatment for Graves’ ophthalmopathy 18 (4%) 1 (1.5%) 0.50
Hypercholesterol 31 (7.5%) 13 (19%) 0.006
Surgeries
    Decompression 100 (24%) 5 (7%) <0.001
    Strabismus 208 (50%) 18 (26%) <0.001
    Levator 88 (21%) 5 (7%) 0.005
    Lower lid retraction 35 (8%) 5 (7%) 1.00
    Blepharoplasty 64 (16%) 7 (10%) 0.28

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