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Br J Ophthalmol 2004;88:1231 doi:10.1136/bjo.2004.oct04atag
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  1. Creig Hoyt, Editor

      KERATOCONUS: ASYMMETRIC DISEASE

      Keratoconus is a non-inflammatory corneal ectasia with bilateral involvement in over 90% of patients. However, in a study of 83 patients diagnosed at presentation Burns and coworkers demonstrated there is significant asymmetry of disease both for corneal shape and visual acuity. Quantitative topographical indices reflected changes in corneal power which correlated best with the impaired visual acuity. See p1252

      BEHÇET’S DISEASE AND SERUM PARAOXONASE ACTIVITY

      Behçet’s disease is a multisystem disorder that is characterised by ocular and skin manifestations as well as genital and oral ulcers. Its aetiology and pathogenesis have yet to be clarified. In a study by Karakucuk and coworkers serum paraoxonase (PON) activity was found to be decreased in the active stage of Behçet’s disease. The authors suggest that endothelial damage and increased PON leucocyte activity in the active stage of the disease may result in …

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