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Br J Ophthalmol 88:1247-1251 doi:10.1136/bjo.2003.039784
  • Clinical science
    • Scientific reports

Blood group related antigens in ocular cicatricial pemphigoid

Table 2

 Immunohistological staining using anti-blood group related antigen Mabs on the conjunctiva of the 22 OCP patients and the 89 normal individuals18

Ph No* % Intensity of staining Intensity of staining
Epithelial cells Goblet cells
Lea S-Lea Leb H-type 2 Lea S-Lea Leb H-type2
OCP, ocular cicatricial pemphigoid; N, normal conjunctiva; Ph, phenotype; Lea, anti-Lea (7LE); S-Lea, anti-sialyl-Lea (NS 19-9); Leb, anti-Leb (2–25 LE); positive reaction from + to +++ represent increasing number of stained cells and intensity staining; NA, not applicable; −, negative staining; *number of individuals; †goblet cells were found only in 5/7 Lea OCP patients; ‡goblet cells were found only in 11/13 Leb OCP patients.
N Lea 17 20 +++ +++ + +++ +++ +
OCP Lea 7 32 +/++ +/++ +/− +/−† +/−† +/− † –†
N Leb 63 70 +++ +++ +++ +++ +++ + +
OCP Leb 13 59 +/− +/++ ++ +/−‡ +/−‡ +/−‡ +‡
N Lec 0 0 NA NA NA NA NA NA NA NA
OCP Lec 2 9
N Led 9 10 ++ ++
OCP Led 0 0 NA NA NA NA NA NA NA NA

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