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Br J Ophthalmol 88:1391-1394 doi:10.1136/bjo.2003.037713
  • Clinical science
    • Scientific reports

Persistency and treatment failure in newly diagnosed open angle glaucoma patients in the United Kingdom

Table 3

 Adjusted hazard rate ratios for risk of therapy failure and therapy discontinuation*

Adjusted hazard ratio 95% CI p Value
*Hazard rate ratios and 95% confidence intervals (CIs) from adjusted Cox regression models.
†Reference group.
Therapy failure
    Latanoprost† 1.00
    Timolol 1.95 1.60 to 2.38 0.005
    Other β blockers 2.28 1.88 to 2.77 0.004
    Carbonic anhydrase inhibitors 3.60 2.92 to 4.44 <0.0001
    Miotics 3.84 2.96 to 4.98 <0.0001
    Sympathomimetics 4.29 3.45 to 5.34 <0.0001
Therapy discontinuation
    Latanoprost† 1.00
    Timolol 1.37 1.06 to 1.78 0.05
    Other β blockers 1.49 1.07 to 2.07 0.01
    Carbonic anhydrase inhibitors 2.52 1.16 to 5.44 <0.0001
    Miotics 3.08 1.20 to 7.88 <0.0001
    Sympathomimetics 2.45 1.16 to 5.19 <0.0001

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