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Br J Ophthalmol 88:1422-1424 doi:10.1136/bjo.2004.048033
  • Clinical science
    • Scientific reports

Epiphora as a side effect of topical mitomycin C

Table 1

 Detailed information on 14 patients with topical MMC treatment

Patient Sex/age Diagnosis No of cycles Epiphora Lacrimal system findings Other signs Treatment Outcome
MM, conjunctival malignant melanoma; PAM, primary acquired melanosis; SCC squamous cell carcinoma.
1 M/49 MM+PAM 3 Yes Normal anatomy Probing and syringing Patent
2 M/75 MM+PAM 1 Yes Normal anatomy Probing and syringing Patent
3 M/83 MM+PAM 2 Yes Normal anatomy Probing and syringing Patent
4 M/44 MM+PAM 1 Yes Common canalicular stenosis Toxoallergic reaction Silicon intubation 4 months Patent
5 M/47 MM+PAM 3 Yes Lower canalicular obstruction None Patent upper canaliculus
6 F/52 MM+PAM 5 Yes Punctum and canalicular stenosis None Watering
7 M/56 MM 1 Yes Punctum stenosis Probing and syringing Patent
8 M/71 MM 2 Yes Punctum stenosis Silicon intubation 2 months Patent
9 F/63 MM 1 Yes Punctum stenosis Silicon intubation 2 months Patent
10 M/62 MM+PAM 4 No Toxoallergic reaction
11 F/51 PAM 6 No
12 M/80 MM 1 No
13 M/49 SCC 5 No
14 F/85 MM+PAM 1 No

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