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Count and size of macular drusen correlated with the parafoveal annular reflex
  1. U Vossmerbaeumer1,
  2. J B Jonas1,
  3. S S Hayreh2
  1. 1Department of Ophthalmology, Mannheim Medical School, Ruprecht-Karls-University of Heidelberg, Germany
  2. 2Departments of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, IA 52242, USA
  1. Correspondence to: Dr U Vossmerbaeumer Universitäts-Augenklinik, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany; urs.vossmerbaeumeraugen.ma.uni-heidelberg.de

https://doi.org/10.1136/bjo.2004.043752

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    Age related macular degeneration is one of the most frequently occurring reasons for decreased vision in the elderly population in Western countries.1 It is divided in a non-exudative form with formation of drusen of the retinal pigment epithelium, and the exudative form with subfoveal chorioretinal neovascularisation and subretinal exudation. Since the subretinal alterations typical for age related macular degeneration may lead to a change in the superficial contour of the retina, it was the aim of this study to evaluate whether the visibility of the macular wall reflex depends on the presence and size of macular drusen as part of age related macular degeneration.

    The study included 47 rhesus monkey (Macaca mulatta) (77 eyes) for which 60° colour fundus photographs were obtained. Only fundus photographs with the central fundus region fully illuminated were evaluated. The entire study group was divided into eyes of monkeys with unilateral …

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    Footnotes

    • Supported by grant EY-1576 from the US National Institutes of Health, in part by unrestricted grants from Research to Prevent Blindness, Inc, New York, USA.

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