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Br J Ophthalmol 2004;88:1498-1499 doi:10.1136/bjo.2003.040519
  • Clinical science
    • Scientific reports

Neurological concomitants of uveitis

  1. J R Smith,
  2. J T Rosenbaum
  1. Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA
  1. Correspondence to: Justine R Smith Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239–4197, USA; smithjusohsu.edu
  • Accepted 25 May 2004

Abstract

Aim: To describe the prevalence and types of neurological disease that occur in association with uveitis.

Methods: Retrospective review of medical records of patients attending a tertiary referral uveitis service over a 15 year period.

Results: Of 1450 patients with uveitis, 115 (7.9%) had neurological disease that was considered to be causally related to the eye inflammation. The most frequent neurological associations were Vogt-Koyanagi-Harada disease, primary central nervous system lymphoma, multiple sclerosis, and herpes virus infections.

Conclusions: Neurological disease is common among patients attending a uveitis service. The distinctive characteristics of the uveal inflammation may be useful in diagnosing the neurological disease.

Footnotes

  • This work was supported by grants from Research to Prevent Blindness (Career Development Award to JRS and Senior Scholar Award to JTR) and the Rosenfeld Family Trust.

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