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Br J Ophthalmol 88:196-198 doi:10.1136/bjo.2003.017715
  • Clinical science
    • Scientific reports

Do selective topical β antagonists for glaucoma have respiratory side effects?

Table 2

Risk of subjects developing new airways obstruction following treatment with unselective and selective topical β antagonist compared to controls

Number of new TBA cases Number of unexposed subjects (group C) Unadjusted rate ratio (95% CI) Adjusted hazard ratio (95% CI)
TBA-U  =  unselective topical β antagonist treated subjects; TBA-S  =  selective topical β antagonist treated subjects.
*p<0.01; **p<0.001.
TBA-U treated subjects 69/2321 (3.0%) 112/9094 (1.2%) 2.30** (1.69 to 3.12) 2.22** (1.63 to 3.02)
TBA-S treated subjects 12/324 (3.7%) 3.06** (1.67 to 5.54) 2.96** (1.63 to 5.36)

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