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Br J Ophthalmol 88:199-203 doi:10.1136/bjo.2003.018234
  • Clinical science
    • Scientific reports

A 12 week study comparing the fixed combination of latanoprost and timolol with the concomitant use of the individual components in patients with open angle glaucoma and ocular hypertension

Table 2

Mean (standard deviation) intraocular pressures (mmHg) by visit (observed cases)

Treatment group
Fixed combination 1st 6 weeks and unfixed combination 2nd 6 weeks (n = 93) Unfixed combination 1st 6 weeks and fixed combination 2nd 6 weeks (n = 97)
*Mean of two intraocular pressure measurements at least one hour apart.
†Diurnal intraocular pressure.
Baseline* 16.9 (2.5) 16.9 (2.3)
Week 6 17.2 (2.8) 16.2 (2.7)
08:00 17.6 (3.1) 16.4 (3.0)
10:00 17.4 (3.1) 16.0 (3.0)
16:00 16.7 (3.1) 16.1 (2.7)
Diurnal 17.2 (2.8) 16.2 (2.7)
Week 12
08:00 15.9 (2.9) 17.1 (3.0)
10:00 15.5 (3.1) 16.9 (2.9)
16:00 15.6 (2.6) 16.6 (3.1)
Diurnal 15.7 (2.7) 16.9 (2.7)

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