Table 2
Ophthalmoscopic, electroretinographic, and histological findings with increasing doses of intravitreal tenecteplase
| Tenecteplase dose (μg) | ||||
|---|---|---|---|---|
| 50 (n = 7) | 150 (n = 5) | 200 (n = 5) | 250 (n = 7) | |
| TRD = tractional retinal detachment; RA = retinal atrophy; RN = retinal necrosis; VF = vitreal fibrosis. | ||||
| Ophthalmoscopy | Normal | Normal | TRD(2) | TRD(3) |
| RA(1) | RN(2) | |||
| Normal(2) | VF(2) | |||
| ERG B-wave amplitude | No reduction | Transitory reduction | Significant reduction | Significant reduction |
| Retinal histology | Normal | Mild damage | Significant damage | Significant damage |
