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Br J Ophthalmol 88:581-582 doi:10.1136/bjo.2003.020305
  • Letter

Prospective case control study on genetic assocation of apolipoprotein ε2 with intraocular pressure

Table 1

Distribution of APOE genotypes and allele frequency

Frequency in APOE characteristic (n (female) mean age in years)
Normals 32 (17) 54.8 OHT 54 (27) 53.3 Pre-OWG 55 (25) 54.4 OWG 41 (20) 56.3
Genotype
    ε2ε2 0 1 (0) 0 0 1 (0) 63.0
    ε2ε3 3 (2) 11 (5) 12 (7) 6 (2) 32 (16) 56.0
    ε2ε4 6 (5) 0 1 (0) 0 7 (5) 53.4
    ε3ε3 14 (6) 32 (17) 24 (12) 27 (15) 97 (50) 54.5
    ε3ε4 9 (6) 9 (5) 18 (6) 8 (3) 44 (18) 53.8
    ε4ε4 0 1 (0) 0 0 1 (0) 43.0
Allele frequency
    ε2 9 13 13 6 41
    ε3 40 84 78 68 270
    ε4 15 11 19 8 53

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