Table 1
Clinicopathological and immunohistochemical features of the retinoblastomas used in the study
| No | Age (years)/sex | Clinicopathological parameters | Chemotherapy | KAI1 immunoreactivity | Ki67 | |
|---|---|---|---|---|---|---|
| % Cells stained | Stain intensity | % cells stained | ||||
| diff = differentiated; Postop = postoperative; chemo = chemotherapy. | ||||||
| 1 | 2/M | Both eyes, (RE) well diff | No | 90 | 3+ | 40 |
| 2 | 5/M | LE, poor diff | No | 90 | 3+ | 37 |
| 3 | 1/F | RE, well diff | No | 90 | 3+ | 63 |
| 4 | 2/M | Both eyes, (RE), well diff | No | 50 | 2+ | 40 |
| 5 | 8/M | LE, poor diff | No | 90 | 3+ | 40 |
| 6 | 4/F | LE, poor diff | No | 80 | 3+ | 60 |
| 7 | 1/F | LE, poor diff | No | 95 | 3+ | 49 |
| 8 | 5/F | RE, poor diff | No | 45 | 2+ | 50 |
| 9 | 1/F | Both eyes, (RE), mod diff | No | 80 | 3+ | 40 |
| 10 | 2/F | Both eyes, RE, mod diff | No | 85 | 3+ | 70 |
| 11 | 2/F | Both eyes, LE, mod diff | No | 40 | 2+ | 66 |
| 12 | 1.5/M | RE, well diff | No | 85 | 3+ | 50 |
| 13 | 7/F | LE, mod diff, No choroidal invasion, surgical end of the optic nerve invaded | Postop chemo 3 cycles | 1 | 0 | 56 |
| 14 | 1/M | RE, poor diff, Pre laminar | No | 20 | 1+ | 60 |
| 15 | 2/F | RE, poor diff, diffuse choroidal invasion, surgical end of optic nerve invaded | Postop chemo 4 cycles | 1 | 0 | 70 |
| 16 | 4/M | Both eyes, LE, poor diff | Postop chemo 4 cycles | 1 | 0 | 70 |
| 17 | 4/F | RE, mod diff, lamina cribrosa | No | 40 | 2+ | 64 |
| 18 | 2/M | RE, poor diff, lamina cribrosa | No | 20 | 1+ | 66 |
| 19 | 1.1 M/F | RE, poor diff, diffuse choroidal invasion and post laminar optic nerve invasion | Postop chemo 6 cycles | 1 | 0 | 80 |
| 20 | 3/M | LE, poor diff, post laminar invasion | Postop chemo 2 cycles | 10 | 1+ | 60 |
| 21 | 4/F | RE, mod diff, focal choroidal invasion | No | 10 | 1+ | 69 |
| 22 | 2/F | RE, poor diff, post laminar | No | 0 | 0 | 70 |
| 23 | 2.5/F | RE, poor diff, diffuse | No | 10 | 1+ | 60 |
| 24 | 3/M | RE, poor diff, post laminar | No | 1 | 0 | 70 |
| 25 | 5/M | RE, poor diff, diffuse choroidal invasion, surgical end of ON invaded | Postop chemo 6 cycles | 1 | 0 | 60 |
| 26 | 5/F | Both eyes,(RE) well diff, pre laminar, focal choroidal invasion | No | 10 | 1+ | 75 |
| 27 | 2/F | Both eyes, (LE) poor diff, diffuse | No | 10 | 1+ | 60 |
| 28 | 2/M | RE, poor diff, post laminar | No | 1 | 0 | 80 |
| 29 | 1/F | Both eyes, (RE) well diff, lamina cribrosa | Preop and postop chemo | 10 | 1+ | 61 |
| 30 | 2/F | Poor diff, diffuse choroidal, post laminar, metastasis to submandibular area | Postop chemo | 1 | 0 | 60 |
