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Br J Ophthalmol 2004;88:635-637 doi:10.1136/bjo.2002.010827
  • Clinical science
    • Scientific reports

Relation between axial length of the eye and hypotensive effect of latanoprost in primary open angle glaucoma

  1. E Arranz-Marquez,
  2. M A Teus
  1. University of Alcalá, Hospital Oftalmológico Internacional de Madrid
  1. Correspondence to: Dr E Arranz-Marquez Chiquinquira 56, Madrid, Spain; esther-arranzole.com
  • Accepted 30 April 2003

Abstract

Aims: To study the effect of axial length on the hypotensive effect of latanoprost in primary open angle glaucoma (POAG) in a prospective, observational study.

Methods: The authors measured axial length and baseline intraocular pressure (IOP) of 109 eyes with POAG, and then repeated the IOP measurements at 1, 3, and 6 months after starting treatment with latanoprost.

Results: The mean IOP level was significantly lower in eyes with a shorter axial length compared with the eyes with a longer axial length both at 3 and 6 months of treatment (p = 0.03 and p = 0.04, respectively, ANOVA).

Conclusion: The hypotensive effect resulting from treatment with latanoprost could be related to ocular axial length.

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