Table 1
Review of literature: sino-orbital invasive Aspergillus fumigatus in immunocompetent individuals
| Case | Age (years), sex | Initial complaint | Had temporal arteritis? | Treated with steroids? | Other treatment | Outcome* | Start in sphenoid† |
|---|---|---|---|---|---|---|---|
| *Time to death is approximated from initial complaint from information in the case reports. If there was no follow up or not enough information given, the case was not included in this table. | |||||||
| †Recorded as “yes” if computed tomography or specific description in reference given. If more than one site involved, the reference was not categorised as having a lesion that started in the sphenoid sinus. | |||||||
| Green et al, 1969 (case 3) | 71, male | Pain | Not reported | Dead 8 months later | |||
| Green et al, 1969 (case 6) | 84, male | Pain | Yes | Yes | Not reported | Dead 6 weeks later | |
| Green et al, 1969 (case 10) (identified as Aspergillus species) | 50, female | Pain | Debridement; amphotericin B | Dead 16 months later | |||
| Hedges & Leung, 1976 | 62, female | Headache then severe pain | Yes | Debridement and amphotericin B | Dead 5 months later | ||
| Yu et al, 1980 | 37, male | Pain | Surgery; amphotericin B; rifampin; flucytosine | Alive at 1 year | |||
| Spoor et al, 1982 | 49, female | Pain | Yes | Amphotericin B and rifampin | Dead 2 months | Yes | |
| Austin et al, 1983 | 77, male | Pain | Yes | Yes | Debridement; amphotericin B | Dead 11 months later | |
| Fuchs et al, 1985 | 48, female | Pain | Surgery; amphotericin B; rifampin | Alive at 1month | Yes | ||
| Lowe & Bradley, 1986 | 74, female | Headache | None | Dead 12 months later | |||
| Bradley et al, 1987 | 74, female | Pain | Yes | Yes | Amphotericin B; flucytosine; ketoconazole; vibunazole | Stable at 2 years | |
| Slavin, 1991 | 65, male | Left sided headache then severe pain | Yes | Amphotericin B | Dead 2 months later | Yes | |
| Heier et al, 1994 (case 3) | 21, female | Painless proptosis | Amphotericin B | Alive at 6 months | |||
| Mauriello et al, 1995 (case 5) | 71, female | Pain | Debridement; amphotericin B then liposomal amphotericin B; local amphotericin B | Dead 4 months later | |||
| Suzuki et al, 1995 | 83, female | Headache | Yes | None | Dead 6 months later | ||
| Massry et al, 1996 | 40, female | Nasal congestion | Debridement; amphotericin B; itraconazole | Stable at 10 years | |||
| Hutnik et al, 1997 | 75, male | Decreased vision | Yes, despite negative biopsy | Yes | Amphotericin B and fluconazole | Dead 2 months later | Yes |
| Streppel et al, 1999 | 50, female | “Acute sinusitis” | Amphotericin B; debridement; liposomal amphotericin B; Postoperative itraconazole | Dead 16 months later | |||
