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Br J Ophthalmol 88:716-718 doi:10.1136/bjo.2003.032698
  • Letter

Apolipoprotein E polymorphism in patients with cataract

Table 2

APOE genotype distributions for control and cataract groups

APOE genotype Observed frequency
Cataracts
Controls (n = 187) Nuclear (n = 77) Cortical (n = 155) Posterior subcapsular (n = 119) Mixed (n = 151) All Cases (n = 502)
p>0.05 for all genotypes when comparing controls and cataracts (all cases) or cataract subgroups. 95% confidence intervals of all odds ratios included 1.0 (no difference).
NO, not observed.
ε2/ε2 0.011 0.013 0.013 0.017 0.020 0.016
ε2/ε3 0.182 0.156 0.181 0.101 0.179 0.157
ε2/ε4 0.021 0.039 0.019 0.008 0.033 0.024
ε3/ε3 0.588 0.636 0.587 0.697 0.596 0.624
ε3/ε4 0.187 0.156 0.194 0.168 0.166 0.173
ε4/ε4 0.011 NO 0.006 0.008 0.007 0.006

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