A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, evaluator masked, multicentre study in Europe

J García-Sánchez; J-F Rouland; D Spiegel; B Pajic; I Cunliffe; C Traverso; J Landry

doi:10.1136/bjo.2003.029330

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Clinical science

Scientific reports

A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, evaluator masked, multicentre study in Europe

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	Abstract	Full	Pdf
Jun 2004	115	162	109
Jul 2004	296	278	124
Aug 2004	139	127	59
Sep 2004	66	98	26
Oct 2004	42	53	30
Nov 2004	49	80	25
Dec 2004	30	41	16
Jan 2005	34	54	4
Feb 2005	32	54	4
Mar 2005	27	53	25
Apr 2005	10	27	9
May 2005	15	31	13
Jun 2005	11	39	10
Jul 2005	16	37	29
Aug 2005	10	29	33
Sep 2005	4	48	23
Oct 2005	13	46	18
Nov 2005	26	49	39
Dec 2005	9	22	14
Jan 2006	12	43	16
Feb 2006	9	38	15
Mar 2006	10	21	14
Apr 2006	14	28	22
May 2006	5	40	18
Jun 2006	5	24	17
Jul 2006	14	34	6
Aug 2006	20	35	18
Sep 2006	22	25	17
Oct 2006	13	23	8
Nov 2006	5	19	10
Dec 2006	4	16	6
Jan 2007	8	17	10
Feb 2007	17	18	12
Mar 2007	25	27	16
Apr 2007	17	9	11
May 2007	16	9	9
Jun 2007	17	8	11
Jul 2007	19	16	11
Aug 2007	14	6	8
Sep 2007	22	13	6
Oct 2007	34	10	21
Nov 2007	12	10	11
Dec 2007	5	0	1
Jan 2008	17	4	7
Feb 2008	4	6	4
Mar 2008	21	2	4
Apr 2008	27	4	7
May 2008	20	4	4
Jun 2008	18	6	11
Jul 2008	15	5	4
Aug 2008	19	7	5
Sep 2008	17	5	6
Oct 2008	15	4	7
Nov 2008	11	2	3
Dec 2008	9	5	6
Jan 2009	19	4	3
Feb 2009	15	3	5
Mar 2009	27	8	3
Apr 2009	24	1	2
May 2009	32	3	8
Jun 2009	40	2	4
Jul 2009	37	3	2
Aug 2009	22	4	4
Sep 2009	7	1	1
Oct 2009	14	3	2
Nov 2009	21	2	4
Dec 2009	17	6	4
Jan 2010	22	1	4
Feb 2010	22	4	7
Mar 2010	8	1	6
Apr 2010	24	3	1
May 2010	16	4	4
Jun 2010	13	4	3
Jul 2010	10	4	3
Aug 2010	16	4	1
Sep 2010	21	1	1
Oct 2010	19	6	5
Nov 2010	13	6	3
Dec 2010	15	8	2
Jan 2011	8	2	1
Feb 2011	9	1	1
Mar 2011	5	10	2
Apr 2011	8	23	0
May 2011	6	8	2
Jun 2011	12	2	1
Jul 2011	11	1	2
Aug 2011	11	2	2
Sep 2011	10	3	2
Oct 2011	19	0	0
Nov 2011	12	5	4
Dec 2011	15	38	11
Jan 2012	20	5	2
Feb 2012	8	6	10
Mar 2012	10	6	5
Apr 2012	14	7	5
May 2012	21	11	7
Jun 2012	33	20	13
Jul 2012	16	9	6
Aug 2012	9	8	7
Sep 2012	15	5	5
Oct 2012	15	42	4
Nov 2012	26	34	7
Dec 2012	31	11	5
Jan 2013	27	40	10
Feb 2013	12	21	4
Mar 2013	28	17	3
Apr 2013	27	15	4
May 2013	26	11	2
Jun 2013	9	9	7
Jul 2013	15	8	3
Aug 2013	16	20	0
Sep 2013	12	11	7
Oct 2013	9	6	1
Nov 2013	17	11	0
Dec 2013	17	24	2
Jan 2014	14	40	3
Feb 2014	16	28	6
Mar 2014	22	15	5
Apr 2014	23	12	11
May 2014	21	20	18
Jun 2014	15	3	4
Jul 2014	20	9	6
Aug 2014	23	12	9
Sep 2014	9	12	4
Oct 2014	9	11	9
Nov 2014	16	29	0
Dec 2014	18	14	5
Jan 2015	19	12	2
Feb 2015	10	1	3
Mar 2015	15	5	3
Apr 2015	60	69	70
May 2015	16	21	15
Jun 2015	15	12	10
Jul 2015	17	9	8
Aug 2015	16	13	13
Sep 2015	18	7	5
Oct 2015	8	7	1
Nov 2015	18	8	3
Dec 2015	17	10	8
Jan 2016	14	6	3
Feb 2016	14	8	4
Mar 2016	10	5	10
Apr 2016	9	6	4
May 2016	17	6	6
Jun 2016	17	7	1
Jul 2016	19	12	3
Aug 2016	12	11	2
Sep 2016	15	12	5
Oct 2016	18	8	3
Nov 2016	17	12	7
Dec 2016	12	5	4
Jan 2017	18	7	0
Feb 2017	4	2	0
Mar 2017	2	10	2
Apr 2017	0	19	5
May 2017	2	18	4
Jun 2017	4	16	6
Jul 2017	14	11	4
Aug 2017	6	6	5
Sep 2017	82	80	1
Oct 2017	213	214	5
Nov 2017	82	80	1
Dec 2017	56	52	1
Jan 2018	51	47	3
Feb 2018	50	49	3
Mar 2018	48	44	2
Apr 2018	63	55	2
May 2018	41	36	1
Jun 2018	46	36	2
Jul 2018	53	49	11
Aug 2018	54	44	5
Sep 2018	56	46	4
Oct 2018	49	39	11
Nov 2018	48	34	0
Dec 2018	46	38	5
Jan 2019	35	27	4
Feb 2019	52	30	7
Mar 2019	43	19	11
Apr 2019	38	24	16
May 2019	41	21	14
Jun 2019	47	32	9
Jul 2019	44	30	5
Aug 2019	46	27	6
Sep 2019	85	42	7
Oct 2019	43	27	4
Nov 2019	47	28	2
Dec 2019	69	41	8
Jan 2020	48	25	6
Feb 2020	85	44	6
Mar 2020	90	30	6
Apr 2020	64	27	8
May 2020	71	33	24
Jun 2020	71	27	6
Jul 2020	67	31	4
Aug 2020	83	36	4
Sep 2020	76	33	6
Oct 2020	70	24	2
Nov 2020	28	11	4
Dec 2020	79	33	13
Jan 2021	50	30	7
Feb 2021	28	6	5
Mar 2021	40	12	7
Apr 2021	75	38	3
May 2021	73	33	5
Jun 2021	28	27	8
Jul 2021	26	26	3
Aug 2021	22	21	3
Sep 2021	14	14	5
Oct 2021	21	9	20
Nov 2021	21	16	19
Dec 2021	25	20	7
Jan 2022	19	6	5
Feb 2022	38	19	7
Mar 2022	19	19	10
Apr 2022	24	16	8
May 2022	38	27	25
Jun 2022	46	34	10
Jul 2022	21	8	3
Aug 2022	31	25	12
Sep 2022	33	21	10
Oct 2022	37	24	9
Nov 2022	33	17	6
Dec 2022	15	11	6
Jan 2023	2	2	5
Feb 2023	8	6	3
Mar 2023	20	4	4
Apr 2023	5	5	6
May 2023	12	5	12
Jun 2023	11	11	4
Jul 2023	11	9	6
Aug 2023	12	10	10
Sep 2023	6	6	14
Oct 2023	10	10	17
Nov 2023	30	29	10
Dec 2023	63	7	4
Jan 2024	23	0	0
Feb 2024	30	2	3
Mar 2024	173	0	1
Total	6821	5205	2041

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