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Br J Ophthalmol 88:877-883 doi:10.1136/bjo.2003.029330
  • Clinical science
    • Scientific reports

A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, evaluator masked, multicentre study in Europe

Table 4

 Adverse event summary

Fixed combination latanoprost/timolol (n = 165) Unfixed combination brimonidine/timolol (n = 167)
n % n %
No adverse event 126 76.4 126 75.5
At least one adverse event 39 23.6 41 24.6
Ocular adverse event(s) 29 17.6 34 20.4
Systemic adverse event(s) 14 8.5 13 7.8
Adverse event(s) related to study medication 12 7.3 31 18.6
Discontinuation due to adverse event(s) 3 1.8 18 10.8
Serious adverse event(s) 4 2.4 1 0.6

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