rss
Br J Ophthalmol 2004;88:998-1001 doi:10.1136/bjo.2003.031948
  • Clinical science
    • Scientific reports

Penetrating keratoplasty: indications over a 10 year period

  1. N Al-Yousuf,
  2. I Mavrikakis,
  3. E Mavrikakis,
  4. S M Daya
  1. Corneoplastic Unit and Eye Bank, Queen Victoria Hospital, East Grinstead, UK
  1. Correspondence to: Mr S M Daya Director and Consultant Ophthalmic Surgeon, Corneoplastic Unit and Eye Bank, Queen Victoria Hospital, East Grinstead, West Sussex RH19 3DZ, UK; sdayacompuserve.com
  • Accepted 5 January 2004

Abstract

Aims: To determine the indications for penetrating keratoplasty (PK) at the Corneoplastic Unit and Eye Bank, UK, a tertiary referral centre, over a 10 year period.

Methods: Records of all patients who underwent PK at our institution between 1990 and 1999 were reviewed retrospectively. Of the 1096 procedures performed in this period, 784 records were available for evaluation (72%).

Results: Regrafting was the most common indication, accounting for 40.9% of all cases. Keratoconus was the second most common indication (15%), followed by Fuchs’ endothelial dystrophy (9.3%), pseudophakic bullous keratopathy (7.6%), and viral keratitis (5.9%), which included both herpes simplex and herpes zoster and showed a statistically significant decreasing trend using regression analysis (p<0.005). Among the regraft subgroup, viral keratitis accounted for 21.2% as the underlying primary diagnosis. The most common cause for graft failure in the regraft subgroup was endothelial failure (41.8%).

Conclusion: Regrafting is the leading indication for PK; viral disease—although declining—is the leading primary diagnosis.

Footnotes

  • Presented in part at “CORNEA 2002 - celebrating 50 years of Eye Banking”, Gatwick, UK, 14 November 2002.

This Article

  1. Abstract
  2. Full text
  3. PDF

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.