Table 1
Summary of clinical features, laboratory results, and visual outcome in 16 patients presenting with clinical findings simulating arn
| Patient | Eye | Initial visualacuity | AC inflam | Retinalvasculitis | Site of retinal necrosis (clock hours) | Final diagnosis | Immune status | PCR analysis for toxoplasmosis | Witmer coefficient(Toxo) | PCR for herpesviridae | Rx | Final visual acuity | Follow up (days) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pyr, pyrimethamine; IT, inferotemporal; A, absent; P, present; Neg, negative; ST, superotemporal; AH, aqueous humour; Pos, positive; LP, light perception; G, granulomatous; SN, superior nasal; Toxo, toxoplasmosis; NG, non-granulomatous; Sul, sulfadiazine; HM, hand motions; CF, counting fingers; Cort, corticosteroids; AmphoB, amphoteracin B, intravenous; No syst D, no systemic disease; NA, not available; IT, immunosuppressive therapy or systemic corticosteroid; AC, anterior chamber inflammation; NP, nasal periphery; Post pole, posterior pole; Inf, inferior; RD, retinal detachment. | |||||||||||||
| 1 | LE | LP | G | P | ST, multifocal, peripheral (6) | Toxo | Thymoma IT | Pos | Not performed | Neg | Sul, Pyr | HM | 20 |
| 2 | RE | 20/100 | A | A | IT, focal (3) | Toxo | Haemopathy, IT | Pos | Neg | Neg | Sul, Pyr | 20/80 | 48 |
| LE | HM | A | A | Posterior, multifocal | 20/200 | ||||||||
| 3 | RE | 20/40 | NG | A | ST, focal, peripheral (4) | Toxo | Heart graft IT | Pos | Neg | Neg | Sul, Pyr | 20/25 | 83 |
| 4 | RE | HM | G | NA | NA | Toxo | Haemopathy | Pos | Neg | Neg | Sul, Pyr, Cort | HM | 8 |
| LE | HM | G | NA | Nasal, multifocal, peripheral (6) | HM | ||||||||
| 5 | LE | HM | G | A | Circumferential, peripheral, (12), RD | Toxo | IT | Pos | Pos | Neg | Sul, Pyr | No LP | 240 |
| 6 | LE | 20/100 | NG | P | Nasal, multifocal, peripheral (6) | Toxo | Hodgkin’s disease IT | Pos | Neg | Neg | Sul, Pyr, Cort | LP | 1242 |
| 7 | RE | HM | G | A | Diffuse, multifocal, peripheral (12) | Toxo | Chronic, lymphocytic leukaemia, IT | Neg Neg Pos | Neg Neg Neg | Pos Not performed Neg | Sul, Pyr, Cort | CF | 67 |
| 8 | LE | 20/40 | G | P | Nasal, multifocal, peripheral, (6), RD | Toxo | IT | Pos | Pos | Neg | Sul, Pyr | 20/100 | 206 |
| 9 | LE | CF | G | P | ST, focal, peripheral (3) | Toxo | No syst D | Not performed | Pos | Neg | Sul, Pyr | 20/50 | 48 |
| 10 | LE | CF | NG | P | IT, focal, peripheral (4) | Toxo | HIV infection | Neg | Neg | Neg | Sul, Pyr | 20/30 | 69 |
| 11 | RE | CF | NG | P | ST, multifocal (6) | Syphilis | HIV infection | Neg | Neg | Neg | Penicillin | 20/25 | 564 |
| LE | 20/50 | NG | P | SN, focal, peripheral (3) | 20/20 | ||||||||
| 12 | RE | HM | NG | P | IT, multifocal (4) | Syphilis | HIV infection | Neg | Neg | Neg | Penicillin | 20/80 | 92 |
| LE | 20/20 | NG | P | IT, multifocal IT | 20/20 | ||||||||
| 13 | LE | CF | Absent | A | ST, IT, and posterior (12) | Aspergillosis | Lymphoma, IT | Not performed | Not performed | Not performed | No therapy | NA | 6 |
| 14 | RE | HM | NG | NA | Inf, focal, mid-periphery (5) | Aspergillosis | Systemic vasculitis IT | Not performed | Not performed | Not performed | Itraconazole AmphoB | CF | 50 |
| 15 | RE | HM | G | A | NP, multifocal (5) | Ocular lymphoma | No syst D | Neg | Neg | Neg | Chemotherapy | 20/100 | 215 |
| 16 | RE | CF | NG | P | Post | Behçet’s disease | No syst D | Neg | Neg | Neg | Cort | 20/25 | 987 |
| LE | 20/200 | NG | P | pole, small foci of diffuse necrosis | 20/20 | ||||||||
