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Alteration of cyclic frequency by botulinum toxin injection in adult onset cyclic esotropia
  1. Y-H Lai1,
  2. D R Fredrick2
  1. 1Department of Ophthalmology, Kaohsiung Medical University Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
  2. 2Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA
  1. Correspondence to: Yu-Hung Lai Department of Ophthalmology, Kaohsiung Medical University Hsiao-Kang Hospital, Kaohsiung Medical University, 100 Zihyou 1st Road, Kaohsiung, 807, Taiwan; yuhung.laimsa.hinet.net

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Cyclic strabismus is an uncommon disorder in which strabismus comes and goes alternately, consistently, and repetitively over a period of time. In a 48 hour cycle, a 24 hour period of orthotropia would be followed by a 24 hour period of constant strabismus. Cycles of 24 hour1 to 96 hour2 patterns have been reported. Most cases have been described in children, and the aetiology of cyclic strabismus is still speculative.

Case report

A 57 year old woman was referred to Kaohsiung Medical University Hospital with the complaint of a periodic visual fluctuation of a “good day“ and a “bad day” alternately for about 6 months. She had diplopia on bad days. She did not have diabetes or hypertension. There was no history of strabismus, amblyopia, patching therapy, ocular trauma, or oculomotor palsy. She had received …

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