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Clinical science
Scientific reports
Fractionated stereotactic radiotherapy for parasellar meningiomas: a preliminary report of visual outcomes
  1. R S Behbehani1,
  2. T McElveen2,
  3. R C Sergott1,
  4. D W Andrews3,
  5. P J Savino1
  1. 1The Neuroophthalmology Service, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
  2. 2Department of Radiation Oncology, Thomas Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
  3. 3Department of Neurosurgery, Thomas Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
  1. Correspondence to: Raed Behbehani, MD Neuroophthalmology Service, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, USA; r_behbehanihotmail.com

Abstract

Background/aim: Fractionated stereotactic radiotherapy (FSRT) is a new treatment for brain tumours that are close to critical structures, such as the visual apparatus. This study aims to assess the visual outcomes for patients with parasellar meningioma following FSRT.

Methods: A retrospective, non-comparative case series of 13 patients with parasellar meningiomas who were treated in one institution with FSRT between January 1995 and January 2001.

Results: 13 patients (26 eyes) were followed for a mean of 2 years. Visual acuity improved in four eyes (12.5%), remained stable in 18 eyes (75%), and worsened in three eyes (12.5%). Visual field improved in 15 eyes (57%), remained stable in six eyes (23%), and worsened in four eyes (15%). No adverse visual outcome occurred as a result of radiation.

Conclusion: These preliminary findings suggest that FSRT is a safe and effective treatment for parasellar meningiomas.

  • FSRT, fractionated stereotactic radiotherapy
  • MD, mean deviation
  • MRI, magnetic resonance image
  • ONSM, optic nerve sheath meningioma
  • fractionated stereotactic radiotherapy
  • parasellar meningioma
  • visual outcome
  • stereotactic radiosurgery
  • FSRT, fractionated stereotactic radiotherapy
  • MD, mean deviation
  • MRI, magnetic resonance image
  • ONSM, optic nerve sheath meningioma
  • fractionated stereotactic radiotherapy
  • parasellar meningioma
  • visual outcome
  • stereotactic radiosurgery

https://doi.org/10.1136/bjo.2004.051979

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    Footnotes

    • The authors have no proprietary interest in any of the instruments used or any other aspect of this study.

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