I read with great interest the letter by Doft et al¹ suggesting amikacin to be a better alternative to ceftazidime, in response to the article by Galloway et al,² that suggested the converse. I would like to suggest that ciprofloxacin is a better alternative to both these drugs. There are certain points that I would like to mention to support my statement.

(1) It has been shown that vancomycin and ceftazidime are incompatible upon mixing, with precipitate formation.³ In addition, Kwok et al have suggested ceftazidime to be relatively ineffective owing to its higher rate of precipitation in the vitreous at body temperature resulting in a …