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Br J Ophthalmol 2005;89:249-250 doi:10.1136/bjo.2004.054007
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Ciprofloxacin in endophthalmitis: an alternative to ceftazidime and amikacin!

  1. V Vedantham
  1. Correspondence to: V Vedantham Retina-Vitreous Service, Aravind Eye Hospital and PG Institute of Ophthalmology, 1 Anna Nagar, Madurai, Tamil Nadu, India 625020; drvasumathyyahoo.com
  • Accepted 13 July 2004

I read with great interest the letter by Doft et al1 suggesting amikacin to be a better alternative to ceftazidime, in response to the article by Galloway et al,2 that suggested the converse. I would like to suggest that ciprofloxacin is a better alternative to both these drugs. There are certain points that I would like to mention to support my statement.

(1) It has been shown that vancomycin and ceftazidime are incompatible upon mixing, with precipitate formation.3 In addition, Kwok et al have suggested ceftazidime to be relatively ineffective owing to its higher rate of precipitation in the vitreous at body temperature resulting in a …

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