Table 4
Stage I, IE lymphoma (n = 117) and association of alternative definitions of plasmacellular differentiation and development of local tumour recurrence, systemic disease, and death related to lymphoma
| Number of markers positive for definition of plasmacellular differentiation | Development of local tumor recurrence | Development of systemic disease | Death related to lymphoma | |||
|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | |
| RR (95% CI) | OR* (95% CI) | RR (95% CI) | OR* (95% CI) | HR (95% CI) | HR* (95% CI) | |
| RR, relative risk (from cross tabulation); OR, odds ratio (from logistic regression); HR, hazard ratio (from Cox regression); | ||||||
| *Adjusted for age at diagnosis and MIB1 (⩽, > 10%). | ||||||
| **Statistically significant (p value < 5%). | ||||||
| †These definitions did not yield different results on this dataset. | ||||||
| ⩾1 or 2† | 1.10 (0.56 to 2.15) | 0.93 (0.36 to 2.40) | 1.77** (1.06 to 2.98) | 1.38 (0.44 to 4.38) | 1.69 (0.49 to 5.84) | 1.10 (0.29 to 4.12) |
| ⩾3 | 0.98 (0.49 to 1.94) | 0.77 (0.29 to 2.02) | 1.65 (0.99 to 2.78) | 1.01 (0.31 to 3.30) | 1.20 (0.34 to 4.28) | 0.70 (0.18 to 2.79) |
| ⩾4 | 1.17 (0.55 to 2.46) | 1.08 (0.38 to 3.05) | 1.73** (1.04 to 2.90) | 1.37 (0.38 to 4.94) | 1.16 (0.24 to 5.54) | 0.98 (0.19 to 5.07) |
