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Br J Ophthalmol 2005;89:521 doi:10.1136/bjo.2005.bjmay05atag
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  1. Creig Hoyt, Editor

      LIMBAL EPITHELIAL CRYPTS

      Most self renewing tissues are served by stem cells. Stem cells are usually confined to their “niche,” a specific location within the organ where the microenvironment supports and maintains these cells. Dua and co-workers have re-evaluated the microanatomy of the corneal limbus and describe an anatomical structure that they termed the limbal epithelial crypt which appears to be a stem cell niche. See p 529

      ANTI-TNF-α THERAPY FOR SIGHT THREATENING UVEITIS

      In patients with uveitis and Behçet’s disease, tumour necrosis factor alpha (TNF-α) levels are raised in serum and aqueous humour. The cytokine TNF-α is an important factor in the pathogenesis of uveitis. Lindstedt and co-workers describe 13 patients with serious sight threatening uveitis treated …

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