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Br J Ophthalmol 2005;89:540-542 doi:10.1136/bjo.2004.058230
  • Clinical science
    • Scientific reports

Intraocular pressure variability in patients who reached target intraocular pressure

  1. F K Malerbi,
  2. M Hatanaka,
  3. R M Vessani,
  4. R Susanna, Jr
  1. Glaucoma Department, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
  1. Correspondence to: Fernando Korn Malerbi Glaucoma Department, University of Sao Paulo School of Medicine, Sao Paulo, Brazil, Rua Capote Valente 171 Ap 122, São Paulo, SP, Brazil, 05409-000; marcelohatanakauol.com.br
  • Accepted 23 October 2004

Abstract

Aim: To assess the intraocular pressure (IOP) variability in patients with primary open angle glaucoma (POAG) under clinical treatment who reached an established target pressure based on isolated office readings.

Methods: Retrospective analysis of 65 eyes from 65 POAG patients under clinical therapy who submitted to modified diurnal tension curve (mDTC) (measurements at every 3 hours between 8 am and 5 pm) followed by a water drinking test (WDT). All subjects had established target IOP ≤15 mm Hg at 11 am or 2 pm. IOP variability during mDTC or WDT was evaluated.

Results: mDTC revealed IOP measurements ≥17 mm Hg in 16 of 65 eyes (24.6%). Nine eyes (13.8%) presented values ≥18 mm Hg. The highest IOP detected by mDTC was 20 mm Hg in one patient (1.5%). WDT demonstrated IOP values ≥17 mm Hg in 32 of 65 eyes (49.2%). 22 eyes (33.8%) presented values ≥18 mm Hg after water ingestion. Moreover, IOP levels ≥20 mm Hg were observed in 14 eyes (21.5%).

Conclusion: A great percentage of POAG patients undergoing clinical treatment and with IOP control based on single office measurement present significantly higher IOP measurements when performing mDTC and, especially, the WDT.

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