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Br J Ophthalmol 89:911-916 doi:10.1136/bjo.2004.059089
  • Laboratory science - Extended reports

Generation of transgenic mice with mild and severe retinal neovascularisation

Table 1

 Characterisation of retinal vasculature in the transgenic mouse lines

Retinal vasculature characteristics Line 029 Line 050/056 Line 094
*Other pathological features observed through clinical and histological examinations.
Capillary non-perfusion + + +
Microaneurysms + + +
Venous dilatation + +
Tortuosity of blood vessels + +
Haemorrhages ± ++ ++
Neovascularisation + ++ ++
Preretinal haemorrhage + ++
Vitreous haemorrhage + ++
Fibrovascular proliferation + +
Cataracts* +++ +
Retinal detachment +++ ++

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