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Br J Ophthalmol 2005;89:926-927 doi:10.1136/bjo.2004.052787
  • Letter

Importance of early morning intraocular pressure recording for measurement of diurnal variation of intraocular pressure

  1. P P Syam,
  2. I Mavrikakis,
  3. C Liu
  1. Sussex Eye Hospital, Eastern Road, Brighton BN2 5BF, UK
  1. Correspondence to: Mr C S C Liu Sussex Eye Hospital, Eastern Road, Brighton BN2 5BF, UK; CSCLiuaol.com
  • Accepted 11 November 2004

Intraocular pressure (IOP) is subject to cyclic fluctuations through the day. Diurnal variation in glaucoma was first reported in 1898.1 Duke-Elder and others reported high IOP on awakening.2–6 There is therefore a chance of missing a pressure elevation with single readings.

Phasing is mainly carried out from 0900 to 1800 hours, thereby missing any early morning spikes of IOP. Any delay in the first measurement will miss variations in IOP that are present immediately on wakening.4,7 We carried out a retrospective study, where patients under the care of the senior author (CL) are routinely admitted for phasing in order to obtain an early morning recording of IOP immediately on …

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