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Intraocular pressure (IOP) is subject to cyclic fluctuations through the day. Diurnal variation in glaucoma was first reported in 1898.1 Duke-Elder and others reported high IOP on awakening.2–6 There is therefore a chance of missing a pressure elevation with single readings.
Phasing is mainly carried out from 0900 to 1800 hours, thereby missing any early morning spikes of IOP. Any delay in the first measurement will miss variations in IOP that are present immediately on wakening.4,7 We carried out a retrospective study, where patients under the care of the senior author (CL) are routinely admitted for phasing in order to obtain an early morning recording of IOP immediately on …
Footnotes
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Ethics committee approval: As this was a retrospective study, ethics committee approval was not required.