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Br J Ophthalmol 2005;89:1021-1025 doi:10.1136/bjo.2004.060053
  • Clinical science
    • Extended reports

Effects of combined cataract surgery and trabeculectomy with mitomycin C on ocular dimensions

  1. S K Law,
  2. A M Mansury,
  3. D Vasudev,
  4. J Caprioli
  1. Jules Stein Eye Institute, University of California, Los Angeles, CA, USA
  1. Correspondence to: Simon K Law MD, 100 Stein Plaza #2-235, Jules Stein Eye Institute, Los Angeles, CA 90095, USA; lawjsei.ucla.edu
  • Accepted 2 December 2004

Abstract

Aims: To characterise changes in ocular dimensions after combined cataract operation and trabeculectomy with mitomycin C using separate incisions (combined operation).

Methods: 24 consecutive eyes that had combined operation and 16 eyes that had cataract operation alone were enrolled. The axial lengths before and after operations were determined with non-contact optical coherence biometry. The intraocular pressures (IOP), axial lengths, corneal curvatures, and the expected and observed refractive errors before and after operations were compared.

Results: After a combined operation, mean IOP was significantly reduced from 16.6 (SD 5.8) mm Hg to 10.9 (4.1) mm Hg (p<0.00001), and mean axial length was significantly shortened from 24.10 (0.98) mm to 23.98 (0.96) mm (p<0.00001). The mean axial length reduction after combined operation (117 (57) μm) was significantly larger than the reduction after cataract operation alone (75 (38) μm, p<0.02), and correlated significantly with the postoperative IOP (p<0.002). There was a mean with the rule surgically induced corneal astigmatism of 0.44 (0.83) dioptre by vector analysis, and a significant increase of mean keratometry reading of 0.23 (0.46) dioptre after a combined operation. However, there was no significant difference between the expected and observed refractive errors.

Conclusions: Despite an alteration of the axial length and corneal curvature, the refractive outcome after a combined operation did not differ significantly from the predicted refraction.

Footnotes

  • Competing interests: none declared

  • Ethical approval: This study was approved by the institutional board of the University of California, Los Angeles.

Responses to this article

  • Short and long-term effect of combined cataract and glaucoma surgery with MMC on ocular dimensions
    • Chieh-Chih Tsai,
    • Yen-Ching Lin, Hui-Chuan Kau, Shu-Ching Kao, Wen-Ming Hsu, and Chieh-Chih Tsai
    Br J Ophthalmol published online September 14, 2009
  • Authors' Reply
    • Simon K Law
    Br J Ophthalmol published online September 14, 2009

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