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Lymphoepithelioma-like carcinoma of the eyelid: a report of two cases
  1. W Ho1,
  2. A Taylor1,
  3. E Kemp1,
  4. F Roberts2
  1. 1Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK
  2. 2University Department of Pathology, Western Infirmary, Glasgow, UK
  1. Correspondence to: Dr F Roberts University Department of Pathology, Western Infirmary, Glasgow, UK; fiona.robertsnorthglasgow.scot.nhs.uk

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Lymphoepithelioma-like carcinoma (LELC) of the skin is a rare malignant epithelial neoplasm, which resembles histologically the nasopharyngeal neoplasm of the same name.1,2 Similar tumours have been reported at a variety of sites including salivary gland, tonsil, thymus, stomach, and uterus. Those involving the skin usually present as a papulonodular lesion on the head or neck of patients above 50 years of age. Only one case originating in the eyelid has been previously described.3 We describe a further two cases and discuss the differential diagnosis.

Case 1

A 79 year old man presented with a fusiform swelling occupying the medial half of his right lower lid (fig 1A). This had developed 8 months previously and was gradually increasing in size. An ectropion repair had been performed on this lid 7 years before presentation. The patient underwent excision of the lesion with reconstruction of the lid using a pedicle flap. The excised lesion was submitted for histopathological examination.

Figure 1

 (A) Clinical photograph of case 1 showing a smooth …

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