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Br J Ophthalmol 2006;90:17-19 doi:10.1136/bjo.2005.075887
  • Clinical science
    • Scientific reports

Scanning laser entoptic perimetry for the detection of visual defects associated with diabetic retinopathy

  1. M El-Bradey,
  2. D J Plummer,
  3. D Uwe-Bartsch,
  4. W R Freeman
  1. Department of Ophthalmology, University of California San Diego, Shiley Eye Center, La Jolla, CA 92093, USA
  1. Correspondence to: William R Freeman MD, Jacobs Retina Center, Department of Ophthalmology, Shiley Eye Center; University of California, San Diego, 0946, 9415 Campus Point Drive, La Jolla, CA 92093, USA; freeman{at}eyecenter.ucsd.edu
  • Accepted 2 September 2005

Abstract

Aim: To determine the sensitivity and specificity of entoptic perimetry for diagnosing diabetic retinopathy at all levels of severity.

Methods: A prospective clinical study at the Shiley Eye Center, University of California, and San Diego. 30 patients with photographically documented diabetic retinopathy and 24 controls with a similar age distribution. Sensitivity and specificity of entoptic perimetry were computed for detecting clinically significant macular oedema within the central 120 degree radius of the fovea compared to fundus photographs.

Results: Entoptic perimetry can detect clinically significant diabetic retinopathy with a sensitivity of 0.88 and specificity of 1.00. Entoptic perimetry can detect the earliest stages of diabetic retinopathy with a sensitivity of 0.86.

Conclusion: Scanning laser entoptic perimetry is an effective tool for detecting visual function loss caused by diabetic retinopathy.

Footnotes

  • Funding: Support: NEI E407366 (WRF) and NEI EY11961 (DJP), and RPB Inc, NY, USA.

  • The University of California, San Diego does have intellectual proprietary interest in scanning laser entoptic perimetry.

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