Table 1
Rates of specific adverse events
| AEs, adverse events; CRAO, central retinal artery occlusion; IOP, intraocular pressure; RPE, retinal pigment epithelium; SRH, subretinal haemorrhage. | |
| Values are n (%). | |
| Potential treatment-related AEs | |
| Corneal abrasion | 11 (0.15) |
| Lens injury | 1 (0.01) |
| Endophthalmitis | 1 (0.01) |
| Retinal detachment | 3 (0.04) |
| Other | |
| Mild discomfort | 10 (0.14) |
| Itching | 1 (0.01) |
| Transient raised IOP | 1 (0.01) |
| Subconjunctival haeme | 2 (0.03) |
| Potential drug-related ocular AEs | |
| Inflammation/uveitis | 10 (0.14) |
| Cataract progression | 1 (0.01) |
| Acute vision loss | 5 (0.07) |
| CRAO | 1 (0.01) |
| Other | |
| Increased/new SRH | 4 (0.06) |
| RPE tears | 4 (0.06) |
| Potential drug-related systemic AEs | |
| Blood pressure increase | 15 (0.21) |
| Deep venous thrombosis | 1 (0.01) |
| Transient ischaemic attack | 1 (0.01) |
| Cerebrovascular accident | 5 (0.07) |
| Myocardial infarction | 0 (0) |
| Death | 2 (0.03) |
