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Peripapillary fundus perimetry in eyes with glaucoma
  1. E Convento1,
  2. E Midena2,
  3. M T Dorigo1,
  4. V Maritan1,
  5. F Cavarzeran1,
  6. I A Fregona1
  1. 1Department of Ophthalmology, University of Padova, Padova, Italy
  2. 2Fondazione GB Bietti per l’Oftalmologia, IRCCS, Roma, Italy
  1. Correspondence to: E Convento Department of Ophthalmology, University of Padova, Via Giustiniani, 2, Padova 35128, Italy; enrica_convento{at}yahoo.it

Abstract

Aims: To evaluate, with fundus perimetry, the peripapillary differential light threshold (DLT) in eyes with glaucoma and ocular hypertension (OHT), and compare it with peripapillary retinal nerve fibre layer (RNFL) thickness.

Methods: 35 glaucomatous, 29 OHT and 24 control eyes were included. Peripapillary DLT at 1° from the optic nerve head was quantified with fundus perimetry; peripapillary RNFL thickness was measured over the same area by optical coherence tomography.

Results: Mean (SD) peripapillary DLT was 19.2 (1.7), 17.6 (4.2) and 10.1 (6.9) dB in control, OHT and glaucomatous eyes, respectively (p<0.001). Mean (SD) RNFL thickness was 98.4 (35.3), 83.9 (35.1) and 55.8 (28.2) μm, respectively (p<0.001). Mean peripapillary DLT showed higher sensitivity and specificity in differentiating the three groups compared with RNFL thickness.

Conclusion: Progressive, significant reduction of peripapillary DLT was documented in OHT and glaucomatous eyes compared with controls (p<0.001). DLT reduction parallels RNFL reduction.

  • AROC, area under the receiver operating characteristic curve
  • DLT, differential light threshold
  • IOP, intraocular pressure
  • OCT, optical coherence tomography
  • OHT, ocular hypertension
  • ONH, optic nerve head
  • RNFL, retinal nerve fibre layer
  • ROC curve, receiver operating characteristic curve

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Footnotes

  • Published Online First 29 June 2006

  • Competing interests: None.

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