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During trabeculectomy, tight suturing of the scleral flap to avoid overfiltration may pose a risk of increased intraocular pressure (IOP) and a flat non-functioning bleb. Furthermore, the nylon sutures usually used to reattach the conjunctiva to the limbus may tear out of the conjunctiva and induce an inflammatory reaction. To overcome these problems, investigators have suggested the use of laser suture lysis1 or releasable sutures2 or other types of closure methods, such as staples, tapes and adhesives.3
Quixil (Omrix Biopharmaceuticals, Ramat Gan, Israel) is a human fibrin sealant consisting of two biological components that form a clot within 30 s of placement on the tissue surface. The clot promotes collagen crosslinking and, consequently, wound healing, and is absorbed after a few days. The aim of this study was to determine whether our good preliminary results with Quixil in an animal model could be extrapolated to human eyes.
The study group consisted of five …
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