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Br J Ophthalmol 2006;90:1435-1436 doi:10.1136/bjo.2006.095703
  • Letter

Central retinal vein occlusion in Wegener’s granulomatosis without retinal vasculitis

  1. M Wang,
  2. R N Khurana,
  3. S R Sadda
  1. Doheny Eye Institute, University of Southern California Keck School of Medicine, Los Angeles, California, USA
  1. Correspondence to: S R Sadda Doheny Eye Institute, Keck School of Medicine, University of Southern California, 1450 San Pablo Street DEI 3610, Los Angeles, CA 90033, USA;SSadda{at}doheny.org
  • Accepted 4 June 2006

The classic type of Wegener’s granulomatosis is characterised by necrotising granulomatous lesions of the upper and lower respiratory tracts, generalised focal necrotising vasculitis and glomerulonephritis, whereas the limited type has no renal involvement.1 Ocular manifestations occur in 30–50% of the patients,1 with retinal involvement less frequent and varying from 1 to 13% in the literature.2,3 We report a case of Wegener’s granulomatosis presenting with a central retinal vein occlusion (RVO) without clinical evidence of intraocular inflammation or retinal vasculitis.

Case report

A 22-year-old white man presented with a 1-week history of intermittent obscuration of vision in his right eye. His medical history was remarkable for classic Wegener’s granulomatosis that had been in remission for the past year. His best-corrected visual acuities were 20/25 in the right eye and 20/20 in …

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