rss
Br J Ophthalmol 2006;90:1476-1480 doi:10.1136/bjo.2006.095018
  • Clinical science
    • Extended reports

Randomised controlled study of conjunctival autograft versus amniotic membrane graft in pterygium excision

  1. P Luanratanakorn1,
  2. T Ratanapakorn1,
  3. O Suwan-apichon1,
  4. R S Chuck2
  1. 1Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
  2. 2Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, USA
  1. Correspondence to: R S Chuck Wilmer Ophthalmological Institute, Johns Hopkins University, 255 Woods Building, 600 North Wolfe Street, Baltimore, MD 21287-9278, USA;rchuck1{at}jhmi.edu
  • Accepted 2 June 2006
  • Published Online First 12 July 2006

Abstract

Aim: To determine whether amniotic membrane can be used as an alternative to conjunctival autograft after pterygium excision.

Methods: 287 eyes with either primary or recurrent pterygium were included in this study. All eyes were randomised to undergo conjunctival autograft or amniotic membrane transplantation after pterygium excision by a single surgeon. 106 eyes in primary pterygium and 14 eyes in the recurrent group were treated with conjunctival autograft, and 148 eyes in primary pterygium and 19 eyes in the recurrent group were treated with amniotic membrane transplantation. Patients were followed up at 6 weeks and 6 months after operation. The main outcome measurement was recurrence rate after surgery.

Results: In the conjunctival group, the recurrence rate was 12.3%, 21.4% and 13.1% for primary, recurrent and all pterygia, respectively. In the amniotic membrane group, the recurrence rate was 25.0%, 52.6% and 28.1% for primary, recurrent and all pterygia, respectively. The recurrence rate for all pterygia in the amniotic membrane group was significantly higher than that in the conjunctival group (p = 0.003).

Conclusions: Amniotic membrane graft had a higher recurrence rate than conjunctival autograft. However, it is an alternative choice, especially for advanced cases with bilateral heads or patients who might need glaucoma surgery later.

Footnotes

  • Published Online First 12 July 2006

  • Funding: This study was supported by an invitation grant from the Faculty of Medicine, Khon Kaen University.

  • Competing interests: None declared.

This Article

  1. Abstract
  2. Full text
  3. PDF
  4. All Versions of this Article:
    1. bjo.2006.095018v1
    2. 90/12/1476 most recent

Services

  1. Email this link to a friend
  2. Alert me when this article is cited
  3. Alert me if a correction is posted
  4. Alert me when eletters are published
  5. Article Usage Statistics
  6. Similar articles in this journal
  7. Similar articles in Web of Science
  8. Similar articles in PubMed
  9. Add article to my folders
  10. Download to citation manager
  11. Request permissions

Responses

  1. Submit a response
  2. No responses published

Social bookmarking

Register for free content


Free sample
 This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
View free sample issue >>

Free archive
The full back archive is now available for BJO. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006, back to volume 1 issue 1.
Register to access the free archive >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.