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Br J Ophthalmol 90:324-327 doi:10.1136/bjo.2005.079624
  • Clinical science
    • Extended reports

Repeat penetrating keratoplasty: indications, graft survival, and visual outcome

  1. H Al-Mezaine1,2,
  2. M D Wagoner2,
  3. and the King Khaled Eye Specialist Hospital Cornea Transplant Study Group*
  1. 1Department of Ophthalmology, King Saud University, Kingdom of Saudi Arabia
  2. 2Anterior Segment Division, Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia
  1. Correspondence to: Michael D Wagoner MD, King Khaled Eye Specialist Hospital, PO Box 7191, Riyadh 11462, Kingdom of Saudi Arabia; michaelwagoner625{at}yahoo.com
  • Accepted 3 November 2005

Abstract

Aim: To determine graft survival and visual outcome after repeat penetrating keratoplasty (PKP).

Methods: Retrospective review of the medical records patients who underwent repeat PKP at the King Khaled Eye Specialist Hospital (KKESH) between 1 January 1991 and 31 December 2002.

Results: 243 repeat PKP performed in 210 eyes of 208 patients, who had also had initial PKP at KKESH, were included in the study. The mean follow up was 43 months (range 1–170). At the most recent examination, 114 (54.3%) grafts were clear. The overall survival rate was 98% at 1 year, 83% at 2 years, and 49% at 5 years. The best graft survival was in eyes with an original diagnosis of keratoconus (93.8%) and the worst was in eyes with Fuchs’ dystrophy (23.1%). Overall, 29.6% of eyes achieved a final visual acuity greater than 20/200, while only 4.8% were 20/40 or better. The best visual prognosis was in eyes with an original diagnosis of stromal dystrophy and keratoconus.

Conclusion: Although the prognosis for repeat PKP is poorer than that of initial PKP, reasonable outcomes can be obtained with repeat PKP with careful case selection.

Footnotes

  • * Listed at end of text.

  • Competing interests: none declared